Nosocomial Challenge

applications

SEM image of bacteria (S. epidermidis) attached to an untreated titanium surface.

Implantable medical device infections are a significant clinical problem.  Implant-borne infections can lead to debilitating and potentially fatal complications such as, sepsis, meningitis and osteomyelitis.  Once colonized, devices must be removed and replaced via complicated multi-visit procedures, and the patient is exposed to large doses of antibiotics.  Despite the high costs of these revisions, there is no reimbursement for treatment of iatrogenic infections.  Therefore, an effective antimicrobial treatment can improve patient outcomes, reduce hospital costs and effectively differentiate a product line.